About: Maturation-Promoting Factor

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An Entity of Type : about:c0079805#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
label	maturation-promoting factor vps45 clic4 rln1 msln hist1h1b
sameAs	HIST1H1B VPS45 mesothelin\|MSLN CLIC4 gene\|CLIC4 RLN1 gene\|RLN1
COEXISTS_WITH	Phosphotransferases Mitogen-Activated Protein Kinases Serum Albumin, Bovine MOS pp39 Serine/Threonine Kinase RMS sorafenib CDC25C\|RASGRF1 Tyrosine 3-Monooxygenase\|TH
ASSOCIATED_WITH	Adenoid Cystic Carcinoma
schema:identifier	3009 11311 10232 25932 6013 c0079805
ISA	Phosphotransferases
INHIBITS	Phosphotransferases Phosphoric Monoester Hydrolases
PART_OF	Cells Oocytes Human
CAUSES	Mitosis Contraction Meiosis egg activation Hibernation Chromosome Condensation nuclear envelope disassembly
INTERACTS_WITH	Cells Oocytes Mitogen-Activated Protein Kinases Ions WEE1 cyclin B1\|CCNB1 Proliferating Cell Nuclear Antigen\|PCNA CDC2 Protein Kinase\|CDK1\|POLD1 M NOS MELK gene\|MELK 1-methyladenine Elongation Factor 1gamma
STIMULATES	Oocytes Antibodies Mitogen-Activated Protein Kinases Potassium Phosphorylation Human Chorionic Gonadotropin\|CGA\|HTC2\|CGB5 Protein Biosynthesis MONOPHENOL MONOOXYGENASE\|TYR Protein phosphatase CDC2 Protein Kinase\|CDK1\|POLD1 Phosphorus, Dietary RNA, Messenger, Maternal MELK gene\|MELK
AFFECTS	Cell Nucleus Cell physiology Cell Cycle Phosphorylation oocyte maturation Protein Biosynthesis Spermatogenesis Cell division phases Polyadenylation
compared_with	Maturation-Promoting Factor
DISRUPTS	Homeostasis Microtubules Protein Biosynthesis microtubule binding
ADMINISTERED_TO	C0030705 Oocytes Ovum Rattus norvegicus
AUGMENTS	Embryo Muscle Cell Cycle Meiosis Phase Transition
PRODUCES	CAMP
NEG_AUGMENTS	Chromosome Condensation
NEG_COEXISTS_WITH	MOS gene\|MOS
NEG_STIMULATES	Oocytes Progesterone
is NEG_LOCATION_OF of	Ovum
is LOCATION_OF of	Embryo Inferior Colliculus Cytoplasm Cell Nucleus C0030705 Oocytes member

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