About: insulin receptor substrate 1 protein|INSR

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An Entity of Type : about:c0123658#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp bacs gngm insulin receptor substrate 1 protein\|INSR
label	insulin receptor substrate 1 protein\|INSR insulin receptor substrate 1 protein\|IRS1 insulin receptor substrate 1 protein akt1 insulin receptor substrate 1 protein\|IARS ins irs1 insulin receptor substrate 1 protein\|INS insr insulin receptor substrate 1 protein\|AKT1 insulin receptor substrate 1 protein\|PIK3CA\|PIK3CB\|PIK3CD\|PIK3CG insulin receptor substrate 1 protein\|FOXO1 iars
sameAs	Insulin Receptor\|INSR IRS1 Proto-Oncogene Proteins c-akt\|AKT1 IARS Insulin\|INS
http://semmed.demo...com/terms#part_of	Cytoplasm Pancreas Kidney Muscle Liver Insulin-Like Growth Factor I Membrane Insulin\|INS Rattus norvegicus Hepatic Stroma
http://semmed.demo...s#associated_with	Hypertensive disease Obesity Neoplasm progression Diabetes Mellitus, Non-Insulin-Dependent Insulin Resistance Diabetes, Gestational Polycystic Ovary Syndrome Glucose Intolerance Carcinoma of Nasopharynx insulin sensitivity Squamous cell carcinoma of esophagus
http://semmed.demo....com/terms#causes	Apoptosis Solid tumor Insulin Resistance
http://semmed.demo...terms#location_of	Transcriptional Activation Protein Expression Polymorphism, Genetic mRNA Expression
http://semmed.demo...ms#interacts_with	Cells multicatalytic endopeptidase complex Epithelial Cells Insulin\|INS Proto-Oncogene Proteins c-akt\|AKT1 Phosphotransferases Tyrosine Blood Glucose Adrenergic Receptor Somatomedins Diethylnitrosamine Insulin-Like-Growth Factor I Receptor OGT Insulin Receptor\|INSR PIN1 Ribosomal Protein S6 insulin receptor tyrosine kinase CUL5 gene\|CUL5
http://semmed.demo...com/terms#affects	Homeostasis Signal Transduction Muscle - Striated (Skeletal) (MMHCC) Cell Proliferation cell transformation Signal Pathways Bone Diseases osteoblast differentiation Cell Adhesion mRNA Expression cellular metabolism bone metabolism phosphoinositide binding Organ Survival
http://semmed.demo...rms#coexists_with	Lipids Insulin\|INS Somatomedins
http://semmed.demo...om/terms#inhibits	Insulin\|INS Proto-Oncogene Proteins c-akt\|AKT1 TNF protein, human\|TNF Ubiquitin protein tyrosine phosphatase 1B MUT\|PIK3CA PER2 protein, mammalian protein kinase R
http://semmed.demo.../terms#stimulates	Cells FRAP1 protein, human\|MTOR MAPK8 gene\|MAPK8 Insulin\|INS Proto-Oncogene Proteins c-akt\|AKT1 Interleukin-6

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