About: GRAP2

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An Entity of Type : about:9402#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp gngm Semmed Gene GRAP2
label	GRAP2 GRAP2 protein, human\|GRAP2 grap2 GRAP2 gene\|GRAP2
sameAs	GRAP2 (NIH - Gene)
terms:part_of	Human Mus
terms:isa	Proteins Adaptor Signaling Protein
terms:location_of	Ectopic Expression
terms:interacts_with	TRANSCRIPTION FACTOR T-Lymphocyte BCR gene\|BCR XYLT2 growth factor receptor-bound protein 2\|GRB2 ORC3L protein, human\|ORC3 CBL gene\|CBL Src homology 2 domain-containing, transforming protein 1\|SHC1 BCR gene\|BCR ITK gene\|ITK SH2 domain-containing leukocyte protein, 76-kDa hematopoietic progenitor kinase 1 growth factor receptor-bound protein 2\|GRB2 VAV1 protein, human\|VAV1 ORC3L protein, human\|ORC3
terms:affects	Transcription, Genetic T-Cell Activation cellular metabolism
terms:inhibits	proto-oncogene protein Spi-1 SPI1 SPIB
terms:stimulates	T-Lymphocyte Interleukin-2 MAP4K1 gene\|MAP4K1
terms:augments	Transcription, Genetic Transcriptional Activation Signal Transduction
terms:administered_to	Jurkat Cells
schema:identifier	9402 C0914970\|9402 C1415284\|9402
PART_OF	Human
INTERACTS_WITH	TRANSCRIPTION FACTOR T-Lymphocyte growth factor receptor-bound protein 2\|GRB2 ORC3L protein, human\|ORC3 Src homology 2 domain-containing, transforming protein 1\|SHC1 SH2 domain-containing leukocyte protein, 76-kDa
STIMULATES	T-Lymphocyte Interleukin-2
AFFECTS	Transcription, Genetic T-Cell Activation
ADMINISTERED_TO	Jurkat Cells
is type of	GRAP2
is sameAs of	mitogen-activated protein kinase p38 Pituitary Adenylate Cyclase Activating Polypeptide 38 Mitogen-Activated Protein Kinase 14 Mitogen-Activated Protein Kinase 13\|CRK\|MAPK14\|MAPK1\|AIMP2\|GRAP2\|AHSA1\|POLDIP2 CRK protein, human\|CRK GRAP2 protein, human\|GRAP2
is terms:process_of of	Polymorphism, Genetic
is terms:location_of of	Cells Human House mice Saccharomyces cerevisiae B-Lymphocytes Human tissue Tumor cells, malignant Mammalian Cell Jurkat Cells
is terms:interacts_with of	Protein Tyrosine Phosphatase CCNDBP1\|NCKIPSD\|MIB1
is terms:coexists_with of	SHC1 protein, human\|SHC1 Galactose
is terms:stimulates of	T-Cell Receptor\|TRBV20OR9-2 Phospholipase C gamma 1 FYN gene\|FYN
is LOCATION_OF of	Cells Mammalian Cell Jurkat Cells
is INTERACTS_WITH of	CCNDBP1\|NCKIPSD\|MIB1
is STIMULATES of	T-Cell Receptor\|TRBV20OR9-2

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