About: USP8 gene|USP8

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About: USP8 gene|USP8 Goto Sponge NotDistinct Permalink

An Entity of Type : about:9101#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	Semmed Gene USP8 gene\|USP8
label	USP8 gene\|USP8 Ubiquitin Specific Protease 8\|USP8
sameAs	USP8 gene\|USP8 (NIH - Gene)
terms:part_of	Endosomes Cells C0030705 House mice Pituitary Adenoma ACTH-Secreting Pituitary Adenoma lysosomal membrane
terms:isa	Endopeptidases\|ERVK-7\|ERVK-8\|ERVK-10\|ERVK-9\|ERVK-21\|ERVK-18\|ERVK-25\|ERVK-24\|ERVK-19 Peptide Hydrolases
terms:causes	Signal Transduction Pituitary Adenoma
terms:location_of	Mutation
terms:produces	inhibitors
terms:interacts_with	receptor Ubiquitin Epidermal Growth Factor Receptor Oligodendroglia DNAJB6\|DNAJA2\|DNAJC14 alpha-Synuclein Serine Vascular Endothelial Growth Factor Receptor-2 Proto-Oncogene Protein pp60 (c-src)\|SRC NTRK1 gene\|NTRK1 SHANK3 Epidermal Growth Factor\|EGF RNF41 CHMP5
terms:affects	Endosomes Down-Regulation Growth cell body (neuron) Tyrosine Phosphorylation Cell Survival Cell Proliferation Ubiquitination Autophagy Early endosome Deubiquitination protein ubiquitination cilium biogenesis
terms:coexists_with	SHANK3
terms:inhibits	Growth Factor Receptors alpha-Synuclein Collagen Type IV TARDBP c-erbB-1 Proto-Oncogenes\|EGFR Epidermal Growth Factor\|EGF JTB gene\|JTB
terms:stimulates	Genes T-Cell Receptor\|TRBV20OR9-2 Pro-Opiomelanocortin Deubiquitination NTRK1 gene\|NTRK1 SHANK2 SHANK3 RNF41 JTB gene\|JTB
terms:converts_to	Peptides
terms:associated_with	Neoplasm adenoma Cushing Syndrome Pituitary Neoplasms Infertility, Male Acromegaly Pituitary Adenoma Pituitary-dependent Cushing's disease ACTH-Secreting Pituitary Adenoma Atrial myxoma with lentigines
terms:neg_associated_with	Infertility, Male
terms:disrupts	Ubiquitination Carrier of disorder
terms:neg_part_of	Mus
schema:identifier	C1336848\|9101 C0663052\|9101
is type of	USP8 gene\|USP8
is sameAs of	USP8 gene\|USP8 Ubiquitin Specific Protease 8\|USP8
is terms:process_of of	Mutation Mutate
is terms:part_of of	Tyrosine
is terms:location_of of	Mammals Endosomes Cell surface Cells C0030705 Brain Eye T-Lymphocyte sperm cell Woman Mus Saccharomyces cerevisiae cohort cell body (neuron) Hippocampal Formation

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