About: Endothelin-2|RNASE2

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An Entity of Type : semmed:Gene, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp gngm Endothelin-2\|RNASE2 Semmed Gene
label	Endothelin-2\|RNASE2 RNASE2 RNASE2 protein, human\|RNASE2 Endothelin-1\|RNASE2 RNase 2\|RNASE2 rnase2
sameAs	RNASE2 (NIH - Gene)
http://semmed.demo...terms#location_of	Mutagenesis, Site-Directed
http://semmed.demo...rms#compared_with	OPA1
http://semmed.demo...om/terms#inhibits	CBFA2T1 gene\|RUNX1T1
http://semmed.demo...neg_coexists_with	eosinophil peroxidase
terms:part_of	Human Primates Rodent eosinophil Skin cell
terms:isa	Ribonucleases Endoribonucleases
terms:causes	Apoptosis Transcriptional Regulation
terms:location_of	Transcription, Genetic Transcriptional Activation Trans-Activation (Genetics) Mutagenesis, Site-Directed mRNA Expression ribonuclease activity
terms:produces	Endoribonucleases
terms:interacts_with	Ribosomal RNA CD40 Ligand Ribonucleases melanocyte GATA1 protein, human\|GATA1 SP1 gene\|SP1 eosinophil peroxidase SP1 gene\|SP1 GATA1 protein, human\|GATA1 trap
terms:affects	Inflammation cell body (neuron) Immunity Renal function Pigmentation Species Differences ribonuclease activity
terms:coexists_with	Enzymes Human Chorionic Gonadotropin\|CGA\|HTC2\|CGB5 Chemotactic Factors SCN9A SERPINE2 gene\|SERPINE2
terms:compared_with	RNASE3 Antipsychotic Agents Onconase OPA1
terms:inhibits	Ribosomal RNA Calcitriol CBFA2T1 gene\|RUNX1T1 acute myeloid leukemia 1 protein\|RUNX1T1
terms:stimulates	Phosphorylation Protein Processing, Post-Translational Endoribonucleases ribonuclease k6\|RNASE6 ribonuclease k6
terms:converts_to	synthetic peptide
terms:associated_with	Disease Pathogenesis melanoma Cerebrovascular accident Alcoholic Intoxication, Chronic innate immune response
terms:predisposes	Endothelial dysfunction Vitiligo
terms:higher_than	Onconase
terms:disrupts	Cells Neoplasm Cell Survival
terms:augments	Asthma Metastatic melanoma Pigmentation
terms:neg_produces	Leukocyte Elastase
terms:neg_coexists_with	eosinophil peroxidase
COEXISTS_WITH	Chemotactic Factors
ASSOCIATED_WITH	Cerebrovascular accident
schema:identifier	C0079282\|6036 6036 C1314953\|6036 C0525614\|6036 C0079281\|6036
PART_OF	Human Primates Rodent Skin cell
CAUSES	Apoptosis
INTERACTS_WITH	Ribonucleases melanocyte eosinophil peroxidase
STIMULATES	Endoribonucleases

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