About: FRK

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An Entity of Type : about:2444#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	gngm Semmed Gene FRK
label	FRK FRK protein, human\|FRK FRK gene\|FRK frk ADAM10\|FRK KYAT1\|FRK
sameAs	FRK (NIH - Gene)
terms:part_of	Protoplasm House mice Cytoplasmic Cytosol
terms:isa	Genes Proteins Phosphotransferases Protein Tyrosine Kinase src-Family Kinases\|SRC Proto-Oncogene Protein pp60 (c-src)\|SRC
terms:causes	Cessation of life Stress cytotoxicity Tumorigenicity
terms:location_of	Evolution Transcription, Genetic Transfection
terms:produces	Fusion Protein Sugars
terms:interacts_with	RAP1A\|RABGEF1\|TERF2IP Homologous Gene Cells Oocytes Glucose Gene Family Tumor Suppressor Genes Focal Adhesion Protein-Tyrosine Kinases Fructose Phosphoric Monoester Hydrolases Urokinase Tumor Suppressor Proteins PTEN gene\|PTEN Proto-Oncogene Proteins c-akt\|AKT1 Insulin\|INS SHB
terms:affects	Body tissue Apoptosis Cell Growth Cell Death Cell Cycle Integumentary system Phosphorylation Tyrosine Phosphorylation Cell Proliferation plant growth/development Developmental Process Scaling Receptor Signaling Genomic Stability epithelial cell differentiation phospholipase C activation
terms:coexists_with	DNA Sequence Tumor Suppressor Genes Exons Genome, Plant c-erbB-1 Proto-Oncogenes\|EGFR
terms:compared_with	CDKN3\|NAPSA
terms:inhibits	Phosphotransferases Phospholipase C Proto-Oncogene Proteins c-akt\|AKT1 c-erbB-1 Proto-Oncogenes\|EGFR Insulin\|INS
terms:stimulates	RAP1A\|RABGEF1\|TERF2IP Signal Transduction Pathways 1-Phosphatidylinositol 3-Kinase Isopropyl Thiogalactoside Proto-Oncogene Proteins c-akt\|AKT1 IRS2 protein, human\|IRS2
terms:associated_with	Malignant Neoplasms Malignant neoplasm of breast melanoma Pheochromocytoma Dominant-Negative Mutation
terms:disrupts	Cells Growth Cell Cycle Cell Proliferation
terms:augments	Cell Death kinase activity Neurites
terms:administered_to	NIH 3T3 Cells
terms:neg_part_of	Mammary Neoplasms Abnormal shape
schema:identifier	C1384553\|2444 C1333577\|2444 2444 883\|2444
CAUSES	Stress
INTERACTS_WITH	Gene Family
AFFECTS	Phosphorylation

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