About: growth-differentiation factor 8

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An Entity of Type : about:c1457899#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp bacs gngm growth-differentiation factor 8
label	growth-differentiation factor 8 growth-differentiation factor 8\|PAEP growth-differentiation factor 8\|MSTN paep
sameAs	PAEP\|PREP\|PTPN22
http://semmed.demo...ms#interacts_with	Muscle Fibers
http://semmed.demo...com/terms#affects	Growth
terms:causes	Down-Regulation cell motility
terms:location_of	Gene Expression
terms:interacts_with	Cells Osteoblasts Muscle Fibers Protein-Lysine 6-Oxidase\|LOX DMD\|BEST1 E-Cadherin Protein-Lysine 6-Oxidase\|LOX
terms:affects	Extracellular Matrix Pathogenesis Growth Pregnancy Phosphorylation Osteogenesis Cell Proliferation Steroid biosynthesis Form of muscle Skeletal Development paracrine Bone Resorption bone metabolism response to hormone stimulus ovarian function Muscle Development
terms:coexists_with	RNA
terms:inhibits	Progesterone MAPK3 gene\|MAPK3 MAPK3 gene\|MAPK3 E-Cadherin steroidogenic acute regulatory protein SMAD3 gene\|SMAD3 PTX3 protein\|PTX3 myostatin\|MSTN GDF8 gene\|MSTN PTX3 SMAD3 gene\|SMAD3
terms:stimulates	MAPK14 gene\|MAPK14 mitogen-activated protein kinase p38\|CRK\|MAPK14\|MAPK1\|AIMP2\|GRAP2\|AHSA1\|POLDIP2 mitogen-activated protein kinase p38 Transforming Growth Factor beta connective tissue growth factor MAPK14 protein, human\|MAPK14 Transforming Growth Factor beta Receptors
terms:disrupts	Growth Pregnancy Osteogenesis Cell Proliferation Luteinization
terms:augments	Transcriptional Activation Signal Transduction cell motility
terms:neg_stimulates	CDKN1A\|TCEAL1\|NSG1\|H3F3AP6
terms:neg_part_of	Mus
LOCATION_OF	Gene Expression
schema:identifier	5047 C1457899 C1457899\|5047 C1457899\|2660 c1457899
INHIBITS	E-Cadherin
CAUSES	Down-Regulation cell motility
INTERACTS_WITH	Cells DMD\|BEST1 E-Cadherin
STIMULATES	Transforming Growth Factor beta
AFFECTS	Pathogenesis Growth Form of muscle ovarian function Muscle Development
AUGMENTS	Signal Transduction cell motility
is type of	growth-differentiation factor 8
is http://semmed.demo...terms#location_of of	Mammals Muscle Heart Brain Body tissue Eye Gut Myoblasts Testis Ovary Uterus Mesocricetus auratus Gizzard

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