About: anti-LFA-1 monoclonal antibody

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An Entity of Type : about:imft#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	imft
label	anti-LFA-1 monoclonal antibody anti-lfa-1 monoclonal antibody
terms:part_of	T-Lymphocyte Human Rattus norvegicus Mus House mice Family suidae Lymphocyte thymocyte Leukocytes, Mononuclear
terms:isa	Therapeutic procedure Monoclonal Antibodies Antibodies
terms:causes	Neoplasm progression Infiltration Graft loss
terms:interacts_with	Interleukin-2 Specific antibody Intercellular adhesion molecule 1 ITGAL gene\|ITGAL Intercellular cell adhesion molecule ITGAL gene\|ITGAL
terms:affects	macrophage Antigen-Presenting Cells Injury neutrophil keratinocyte Cytolysis T-Cell Activation Graft Survival Cell-Mediated Cytolysis Acne
terms:treats	Mus
terms:uses	Pharmaceutical Preparations
terms:coexists_with	Monoclonal Antibodies Sirolimus (substance) Lymphokines
terms:compared_with	saline
terms:inhibits	Monoclonal Antibodies cytokine Antigens TNF gene\|TNF Interleukin-2 Tumor Necrosis Factor-alpha\|TNF Phytohemagglutinins\|LBR Immunoglobulins, E Lymphocyte Function-Associated Antigen-1 Selectins Stromal Cell-Derived Factor 1 P-Selectin TNFRSF10B gene\|TNFRSF10B Interleukin-2\|IL2 TNFRSF10B gene\|TNFRSF10B Phytohemagglutinins\|LBR
terms:stimulates	Integrins Lymphocyte Function-Associated Antigen-1 NELFCD
terms:method_of	Induction Allografting
terms:disrupts	Cells Inflammation T-Lymphocyte Transcription, Genetic Leukocytes Cell Proliferation cell motility cytotoxicity Cytolysis Infiltration T-Cell Activation Adhesions Natural Killer Cells lysis Chronic eosinophilic inflammation thymocyte Cellular Infiltration Peripheral Blood Lymphocyte Frozen Sections
terms:administered_to	Animals Rattus norvegicus
terms:neg_part_of	Cells
terms:neg_interacts_with	Superoxides
terms:neg_inhibits	Ionomycin TNFRSF5 gene\|CD40 DHPS gene\|DHPS MS4A1 gene\|MS4A1 CD19 gene\|CD19 ectonucleoside triphosphate diphosphohydrolase 1\|ENTPD1 TNFRSF5 gene\|CD40 PTPRC gene\|PTPRC MS4A1 gene\|MS4A1 ectonucleoside triphosphate diphosphohydrolase 1\|ENTPD1 DHPS gene\|DHPS CD19 gene\|CD19
terms:neg_disrupts	Exocytosis
terms:neg_predisposes	Exhaustion
COEXISTS_WITH	Monoclonal Antibodies
schema:identifier	C0757166

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