About: SPINT2 protein, human|SPINT2

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About: SPINT2 protein, human|SPINT2 Goto Sponge NotDistinct Permalink

An Entity of Type : about:c0668013#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	SPINT2 protein, human\|SPINT2
label	SPINT2 protein, human\|SPINT2 spint2 spint2 protein, human
sameAs	SPINT2 gene\|SPINT2
http://semmed.demo...s#associated_with	Malignant neoplasm of prostate
http://semmed.demo...ms#interacts_with	matriptase hepcidin
http://semmed.demo...om/terms#inhibits	Peptide Hydrolases
http://semmed.demo.../terms#stimulates	Enzyme Precursors matriptase
http://semmed.demo...om/terms#disrupts	invasive growth
terms:causes	Down-Regulation
terms:location_of	Mutation
terms:interacts_with	Cells keratinocyte beta-Galactosidase matriptase hepcidin
terms:affects	Adenocarcinoma
terms:treats	Malignant Neoplasms Human Mus House mice Malignant neoplasm of cervix uteri Endometrial Hyperplasia Endometrium normal
terms:compared_with	SPINT2 protein, human\|SPINT2
terms:inhibits	Hepatocyte Growth Factor\|HGF Peptide Hydrolases Serine Protease trypsin-like serine protease matriptase hepsin\|HPN hepatocyte growth factor activator\|HGF
terms:stimulates	stellate cell Fibroblasts Enzyme Precursors matriptase PRSS8 protein, human\|PRSS8
terms:associated_with	Malignant neoplasm of breast Malignant neoplasm of endometrium Malignant neoplasm of prostate Malignant neoplasm of cervix uteri
terms:neg_affects	Prenatal development
terms:disrupts	Virus Diseases Cell Growth Carcinogenesis Cytokinesis of the fertilized ovum Growth retardation cell activation invasive growth
terms:neg_inhibits	PRSS8 protein, human\|PRSS8
LOCATION_OF	Mutation
ASSOCIATED_WITH	Malignant neoplasm of cervix uteri
schema:identifier	10653 C0668013\|10653 c0668013
INHIBITS	matriptase hepsin\|HPN hepatocyte growth factor activator\|HGF
STIMULATES	Enzyme Precursors matriptase PRSS8 protein, human\|PRSS8
TREATS	Human House mice Malignant neoplasm of cervix uteri
compared_with	SPINT2 protein, human\|SPINT2
DISRUPTS	Cell Growth
NEG_INHIBITS	PRSS8 protein, human\|PRSS8
is type of	SPINT2 protein, human\|SPINT2
is http://semmed.demo...terms#location_of of	Cell membrane
is http://semmed.demo...s#neg_location_of of	apical plasma membrane
is terms:isa of	alpha1-microglobulin
is terms:location_of of	Epithelial Cells Body tissue Cell membrane Caco-2 Cells Testis Breast Cancer Cell Enterocytes
is terms:produces of	Brain Embryonic Stem Cell
is terms:interacts_with of	matriptase hepatocyte growth factor activator\|HGF
is terms:coexists_with of	hepatocyte growth factor activator\|HGF
is terms:compared_with of	SPINT2 protein, human\|SPINT2
is terms:measures of	Enzyme-Linked Immunosorbent Assay
is terms:neg_location_of of	apical plasma membrane
is terms:neg_interacts_with of	PRSS8 protein, human\|PRSS8
is LOCATION_OF of	Caco-2 Cells Enterocytes
is compared_with of	SPINT2 protein, human\|SPINT2
is MEASURES of	Enzyme-Linked Immunosorbent Assay

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