About: Proline-Directed Protein Kinases

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About: Proline-Directed Protein Kinases Goto Sponge NotDistinct Permalink

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Attributes	Values
type	aapp gngm
label	Proline-Directed Protein Kinases proline-directed protein kinases
http://semmed.demo...ms#interacts_with	DNA Sequence
terms:part_of	network Mitotic spindle Neurofilament
terms:isa	Proteins Phosphotransferases PROTEIN KINASE Protein-Serine-Threonine Kinases
terms:causes	Mental Retardation
terms:produces	Tumor Suppressor Proteins
terms:interacts_with	DNA Sequence Neurons Proline MAPT Tyrosine 3-Monooxygenase\|TH tau Proteins\|MAPT microtubule-associated protein 1B\|MAP1B Consensus Sequence Cytidine Triphosphate Caldesmon Synapsins myristoylated alanine-rich C kinase substrate Ribosomal Protein S6 Kinases, 70-kDa\|UBASH3B MAP2 MYB gene\|MYB Tyrosine 3-Monooxygenase\|TH Genes, myb\|MYB microtubule-associated protein 1B\|MAP1B
terms:affects	Nerve Degeneration Cell physiology Phosphorylation integral to membrane Cytoskeleton Catalysis neurodevelopment
terms:coexists_with	Phosphotransferases Protein-Serine-Threonine Kinases ERBB2\|NEU1\|NEURL1 erbB-2 Receptor\|ERBB2
terms:compared_with	MAPK8 gene\|MAPK8
terms:stimulates	Neurons Phosphorylation PC12 Cells
terms:associated_with	Malignant Neoplasms Tumorigenesis Pheochromocytoma Cell Transformation, Neoplastic
terms:neg_associated_with	Alzheimer's Disease
terms:predisposes	Tumorigenesis Cell Transformation, Neoplastic
terms:disrupts	PKA activity
terms:neg_interacts_with	Cells
terms:neg_same_as	MAPK8 gene\|MAPK8
ASSOCIATED_WITH	Tumorigenesis Cell Transformation, Neoplastic
schema:identifier	C0084209 c0084209
CAUSES	Mental Retardation
INTERACTS_WITH	Neurons Proline MAPT tau Proteins\|MAPT microtubule-associated protein 1B\|MAP1B Consensus Sequence Cytidine Triphosphate
AFFECTS	integral to membrane neurodevelopment
PREDISPOSES	Tumorigenesis Cell Transformation, Neoplastic
is terms:isa of	Cyclin-Dependent Kinase 5\|CDK5 Mitogen-Activated Protein Kinases Mitogen Activated Protein Kinase 1 Cyclin-Dependent Kinases Cyclin-Dependent Kinase 5 EPHB2\|MAPK1
is terms:location_of of	Cells Brain Neurons Body tissue Organism Cytosol Inclusion Bodies
is terms:produces of	acid sphingomyelinase
is terms:interacts_with of	Proteins Phosphotransferases Estrogen Receptors MAPT Protein Kinase C tau Proteins\|MAPT CDC2 Protein Kinase\|CDK1\|POLD1 Alar Synapsins CDC2 Protein Kinase\|CDK1
is terms:coexists_with of	Phosphotransferases Cyclin-Dependent Kinase 5
is terms:compared_with of	Phosphotransferases

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