About: 11-deoxyprostaglandin E1

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An Entity of Type : about:eico#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	phsu eico
label	11-deoxyprostaglandin E1 11-deoxyprostaglandin e1
terms:part_of	macrophage
terms:isa	Vasodilator Agents Alprostadil
terms:causes	depolarization Hyperalgesia Contraction
terms:interacts_with	Dinoprostone Prostaglandins E EP4 receptor Glycosides PTGER4
terms:affects	Equilibrium
terms:compared_with	Dinoprostone Iloprost
terms:inhibits	CAMP Extracellular Signal Regulated Kinases alpha-Actin Collagen Type I Intercellular adhesion molecule 1
terms:stimulates	PTGER2\|SPAG11B RNA, Messenger Phosphorylation Adenylate Cyclase Matrix Metalloproteinases PTGER3 WFDC2 protein, human\|WFDC2 adenylate cyclase activity Cyclic AMP EP4 receptor PTGER2\|SPAG11B CPN2\|DBI WFDC2 protein, human\|WFDC2 DBI\|EPO\|EREG
terms:converts_to	Vasoconstrictor Agents
terms:higher_than	Iloprost
terms:neg_affects	Lesion of stomach Entire sympathetic nerve
terms:disrupts	Growth Apoptosis Phosphorylation Chemotaxis
terms:augments	Cells Bone Marrow Cells Osteoclasts Increased adenylic acid
terms:neg_inhibits	Cyclic AMP-Dependent Protein Kinases Intercellular adhesion molecule 1
NEG_AFFECTS	Entire sympathetic nerve
schema:identifier	C0044733 c0044733
ISA	Vasodilator Agents Alprostadil
INHIBITS	CAMP Intercellular adhesion molecule 1
CAUSES	Hyperalgesia
STIMULATES	RNA, Messenger Adenylate Cyclase PTGER3 Cyclic AMP EP4 receptor
AFFECTS	Equilibrium
DISRUPTS	Growth
AUGMENTS	Osteoclasts
NEG_INHIBITS	Intercellular adhesion molecule 1
is terms:location_of of	monocyte Trachea
is terms:interacts_with of	SILV protein, human\|PMEL SILV protein, human\|PMEL
is terms:coexists_with of	TGFB1 protein, human\|TGFB1 TGFB1 gene\|TGFB1
is terms:compared_with of	Dinoprostone butaprost
is terms:inhibits of	KT 5720
is terms:stimulates of	agonists Forskolin
is terms:higher_than of	Dinoprostone
is terms:lower_than of	butaprost
is terms:neg_interacts_with of	Dinoprostone butaprost
is STIMULATES of	Forskolin

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