About: Fusion Proteins, bcr-abl|ABL1|MTTP

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An Entity of Type : about:c0004891#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp Fusion Proteins, bcr-abl\|ABL1\|MTTP
label	Fusion Proteins, bcr-abl\|ABL1\|MTTP bcr abl1 Fusion Proteins, bcr-abl\|BCR Fusion Proteins, bcr-abl Fusion Proteins, bcr-abl\|ABL1 Fusion Proteins, bcr-abl\|CALB2\|CR2\|CD55\|TDGF1\|DHRS4\|PPHLN1 fusion proteins, bcr-abl mttp
sameAs	ABL1 gene\|ABL1 BCR gene\|BCR MTTP gene\|MTTP
http://semmed.demo...com/terms#part_of	PROTEIN KINASE Myeloid Leukemia, Chronic
http://semmed.demo...s#associated_with	Myeloid Leukemia, Chronic
http://semmed.demo....com/terms#causes	Malignant Neoplasms Growth Myeloid Leukemia, Chronic Leukemogenesis
http://semmed.demo...ms#interacts_with	Cells Enzymes K562 Cells
http://semmed.demo...rms#coexists_with	Carcinogens vasodilator-stimulated phosphoprotein JAK2 gene\|JAK2
http://semmed.demo...om/terms#inhibits	HSP90 Heat-Shock Proteins\|HSP90AA1 alantolactone
http://semmed.demo.../terms#stimulates	Phosphotransferases JAK2 gene\|JAK2 STAT5A gene\|STAT5A kinase activity HCK gene\|HCK phosphatase activity CRKL gene\|CRKL
http://semmed.demo...terms#predisposes	Myeloid Leukemia, Chronic Malignant transformation Leukemia, Lymphocytic, Acute
http://semmed.demo...om/terms#disrupts	Growth Translation, Genetic Signal Pathways
http://semmed.demo...om/terms#augments	Plethora
terms:part_of	Cells Cytoplasm Cell Line Phosphotransferases PROTEIN KINASE Cytoplasmic BCR gene\|BCR Myeloid Leukemia, Chronic leukemia Embryonic Stem Cell Leukemia, Lymphocytic, Acute BCR protein, human\|BCR MONONUCLEAR CELLS Proto-Oncogene Protein pp60 (c-src)\|SRC ABL1 gene\|ABL1 Philadelphia Chromosome CNTNAP1 gene\|CNTNAP1 BP2
terms:isa	Oncogene Proteins
terms:causes	Disease Malignant Neoplasms Pathogenesis Cessation of life Down-Regulation Growth Apoptosis Tumorigenesis Cell Death Up-Regulation (Physiology) Cell Survival Cell Proliferation Leukemia, Lymphocytic, Acute, L2 Myeloid Leukemia, Chronic Malignant transformation Chromosomal Instability leukemia Myeloproliferative disease Leukemia, Lymphocytic, Acute Leukemogenesis Acute leukemia Autophagy Undifferentiated leukemia
terms:location_of	Mutation Transcriptional Activation Translation, Genetic Ectopic Expression
terms:produces	Imatinib mesylate Retroviral Vector tyrosine kinase ABL1\|ABL1\|ANPEP\|CTR9\|CHAF1A\|RAB3GAP2\|PIK3R4
terms:interacts_with	Cells Enzymes Leukemic Cell Escherichia coli T-Lymphocyte Proteins Phosphotransferases imatinib

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