About: ribosomal protein S6 kinase, 70kD, polypeptide 2|RPS6KB2

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About: ribosomal protein S6 kinase, 70kD, polypeptide 2|RPS6KB2 Goto Sponge NotDistinct Permalink

An Entity of Type : http://semmed.demo.openlinksw.com/schemas/Gene#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp gngm Semmed Gene ribosomal protein S6 kinase, 70kD, polypeptide 2\|RPS6KB2 Semmed Gene Class
label	ribosomal protein S6 kinase, 70kD, polypeptide 2\|RPS6KB2 RPS6KB2 RPS6KB2\|ZAP70 RPS6KB2 gene\|RPS6KB2 zap70 rps6kb2
sameAs	RPS6KB2\|ZAP70 (NIH - Gene) ZAP70 ZAP70 (NIH - Gene)
terms:part_of	Bone Marrow integral to membrane Hepatic
terms:isa	Proteins Phosphotransferases Protein-Serine-Threonine Kinases Ribosomal Protein S6 Kinases, 70-kDa\|UBASH3B Ribosomal Protein S6 Kinases, 70-kDa\|RPS6KB1 Ribosomal Protein S6 Kinase
terms:causes	Up-Regulation (Physiology)
terms:interacts_with	Amino Acids Cell Line Phosphotransferases PROTEIN KINASE Collagen Sirolimus (substance) Phosphoric Monoester Hydrolases wortmannin Ribosomal Protein S6 Kinases, 70-kDa\|RPS6KB1 FRAP1 protein, human\|MTOR EIF5\|EIF5A
terms:affects	Cell Line Cell Growth anti-apoptosis Cell Cycle Signal Transduction Phosphorylation Translation, Genetic Protein Biosynthesis Mammary Tumorigenesis
terms:coexists_with	Genes IRS1
terms:compared_with	Molecular Chaperones ribosomal protein S6 kinase, 70kD, polypeptide 2\|RPS6KB2
terms:inhibits	Tamoxifen HDAC9 Ribosomal Protein S6 Kinases, 70-kDa\|RPS6KB1 EP300 protein, human\|EP300 EIF5\|EIF5A
terms:stimulates	Fibronectins Insulin\|INS Phosphotransferases kinase activity
terms:associated_with	Malignant neoplasm of breast Mutant Neoplasm progression Intrahepatic Cholangiocarcinoma
terms:neg_affects	Growth Cell Growth
terms:disrupts	kinase activity
terms:augments	Kidney Malignant neoplasm of breast Body tissue
terms:neg_part_of	Mus
terms:neg_coexists_with	Proliferating Cell Nuclear Antigen\|PCNA
schema:identifier	7535 C1138418\|6199 6199 6199\|7535 C1335645\|6199
AFFECTS	Cell Cycle Protein Biosynthesis
is type of	ribosomal protein S6 kinase, 70kD, polypeptide 2\|RPS6KB2
is sameAs of	ZAP-70 Gene\|SULT2A1\|ZAP70 ribosomal protein S6 kinase, 70kD, polypeptide 2\|RPS6KB2\|ZAP70
is terms:process_of of	Translation, Genetic Gene Amplification Linked gene
is terms:part_of of	Membrane Proteins
is terms:location_of of	Cell Nucleus C0030705 Membrane Plants Mus House mice cohort B-Lymphocytes Eukaryota Adrenal Glands Mammalian Cell nucleocapsid location Breast Cancer Cell Trees Arabidopsis lyrata Raphanus
is terms:produces of	Cell Line

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