About: MAP3K5

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An Entity of Type : semmed:Gene, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp gngm MAP3K5 Semmed Gene
label	MAP3K5 TNF receptor-associated factor 2\|MAP3K5 MAP Kinase Kinase Kinase 5\|MAP3K5 MAP3K5 gene\|MAP3K5 Protein Phosphatase 2A Regulatory Subunit PR53\|MAP3K5 TNF receptor-associated factor 1\|MAP3K5 map3k5
sameAs	MAP3K5 (NIH - Gene)
http://semmed.demo...s#associated_with	Complication Pancreatic carcinoma Injury Inflammatory Response melanoma Pancreatitis Teratogenesis Diabetic Nephropathy innate immune response Renal fibrosis Ureteral obstruction multiple pathologies
http://semmed.demo....com/terms#causes	Diabetes Apoptosis No past history Cell Death Signal Transduction Stress
http://semmed.demo...om/terms#produces	Interleukin-17
http://semmed.demo...ms#interacts_with	Pharmaceutical Preparations Proteins MAPK8 gene\|MAPK8 Proto-Oncogene Proteins c-akt\|AKT1 Phosphotransferases Fibroblasts Chondrocytes Alkaline Phosphatase 14-3-3 Proteins COX7A2L gene\|COX7A2L S100B MLL gene\|KMT2A tributyltin MAP2K6 gene\|MAP2K6 di-n-butyltin
http://semmed.demo...com/terms#affects	Pathogenesis Cessation of life Body tissue Apoptosis Systemic arterial pressure Tumorigenesis Cell Death Signal Transduction Phosphorylation biological adaptation to stress Stress Impaired cognition Cell Survival unfolded protein response caspase activation Cell Cycle Progression cell invasion Neurophysiology - biologic function Adverse event Congenital Heart Defects Vascular Permeability Contact hypersensitivity Skeletal tissue Endochondral bone formation mRNA cleavage
http://semmed.demo...rms#coexists_with	Reactive Oxygen Species TNF protein, human\|TNF Ubiquitin Calcineurin HGH-V protein, human\|GH2
http://semmed.demo...om/terms#inhibits	RNA, Small Interfering multicatalytic endopeptidase complex Collagen Thioredoxin MAPK14 protein, human\|MAPK14 MAP3K7 gene\|MAP3K7 thioredoxin reductase PER2 protein, mammalian PDPK1 gene\|PDPK1
http://semmed.demo.../terms#stimulates	Cells Cell Line MAPK8 gene\|MAPK8 CRK protein, human\|CRK NF-kappa B Phosphorylation mitogen-activated protein kinase p38 Signal Transduction Pathways Endothelial Cells Alkaline Phosphatase Myocytes, Smooth Muscle MAPK14 protein, human\|MAPK14 MAP2K3 protein kinase B gamma\|AKT3 IRF3 gene\|IRF3

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