About: IFIT3

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An Entity of Type : http://semmed.demo.openlinksw.com/schemas/Gene#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp gngm IFIT3 Semmed Gene Semmed Gene Class
label	IFIT3 IFIT3\|TNFRSF1A\|ARHGEF5\|SQSTM1\|STIP1 tnfrsf1a IFIT3 gene\|IFIT3 sqstm1 arhgef5 ifit3 stip1
sameAs	TNFRSF1A (NIH - Gene) IFIT3 (NIH - Gene) ARHGEF5\|TIMELESS\|HAVCR1 (NIH - Gene) STIP1 (NIH - Gene) SQSTM1 STIP1 tumor necrosis factor receptor 1A\|TNFRSF1A ARHGEF5 gene\|ARHGEF5 SQSTM1 (NIH - Gene)
http://semmed.demo...com/terms#part_of	Family suidae
http://semmed.demo....com/terms#causes	Apoptosis
http://semmed.demo...com/terms#affects	Cell physiology
http://semmed.demo.../terms#stimulates	NF-kappa B Interferon-beta Apoptosis Regulator
terms:part_of	Cytoplasm Human House mice Family suidae Hepatic transforming virus
terms:causes	Apoptosis Cell Death
terms:location_of	Ectopic Expression
terms:produces	FRAGMENTS
terms:interacts_with	Genes Toxin Cell Line B-Lymphocytes Breast Cancer Cell STAT5A protein, human\|STAT5A Protein Kinase C-delta ORNITHINE CARBAMOYLTRANSFERASE\|PLXNA2 CXC chemokine IP-10\|CXCL10 IFIT1\|PSMC1\|CDKL2\|CCDC91 lipoteichoic acid TOLLIP protein, human\|TOLLIP ORNITHINE CARBAMOYLTRANSFERASE\|PLXNA2 CXC chemokine IP-10\|CXCL10 IFIT2 STAT5A gene\|STAT5A TOLLIP protein, human\|TOLLIP
terms:affects	Malignant Neoplasms Body tissue uptake Cell physiology Little's Disease Neuraxis monocyte differentiation
terms:coexists_with	genetic locus Immunoglobulin Isotypes DNA, Double-Stranded Antibodies, Antinuclear IFIT1\|PSMC1\|CDKL2\|CCDC91 GLI2 gene\|GLI2 Sm antibody
terms:inhibits	Polymerase\|ERVK-9\|ERVK-19\|ERVK-11
terms:stimulates	Lipopolysaccharides NF-kappa B monocyte Interleukin-4 human leukocyte interferon\|IFNA1 Interferon-beta Interferon Alfa-2b\|IFNA1 Apoptosis Regulator
terms:associated_with	Malignant Neoplasms Chronic Obstructive Airway Disease Ankylosing spondylitis
terms:neg_associated_with	Pancreatic Ductal Adenocarcinoma
terms:predisposes	Tumorigenesis Vasculitis Chronic graft-versus-host disease
terms:disrupts	Phosphorylation Ischemia JNK activity
terms:augments	Apoptosis anti-apoptosis Translational Repression Liver tissue
terms:neg_interacts_with	IFIT1\|PSMC1\|CDKL2\|CCDC91
terms:neg_predisposes	Pathogenesis
LOCATION_OF	Ectopic Expression
COEXISTS_WITH	Immunoglobulin Isotypes DNA, Double-Stranded Antibodies, Antinuclear Sm antibody
NEG_ASSOCIATED_WITH	Pancreatic Ductal Adenocarcinoma

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