About: CYP8B1 gene|CYP8B1

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An Entity of Type : about:1582#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	aapp Semmed Gene CYP8B1 gene\|CYP8B1
label	CYP8B1 gene\|CYP8B1 Sterol 12-alpha-Hydroxylase\|CYP8B1 CYP8B1 cyp8b1 CYP8B1 protein, human\|CYP8B1
sameAs	CYP8B1 (NIH - Gene)
terms:part_of	Human Rattus norvegicus Mus House mice Hepatic
terms:isa	Therapeutic procedure Enzymes Mixed Function Oxygenases
terms:causes	Dissociation
terms:location_of	Transcription, Genetic mRNA Expression cAMP response element binding protein binding
terms:interacts_with	Escherichia coli Hepatocyte Bile Acids Cholic Acid beta-Galactosidase luciferin Bile Salts Taurocholic Acid cholate Cholesterol 7-alpha-Monooxygenase\|CYP7A1
terms:affects	feedback inhibition glucose homeostasis Transcriptional Repression Chromosomes, Human, Pair 9 cholesterol metabolism
terms:coexists_with	RNA, Messenger CYP2B6 SULT2A1 hyocholic acid
terms:inhibits	Bile Acids liver X receptor alpha Non-HDL cholesterol
terms:stimulates	Cholic Acid Cholesterol 7-alpha-Monooxygenase\|CYP7A1 ABCB11 beta-muricholic acid Cholesterol 7-alpha-Monooxygenase\|CYP7A1
terms:associated_with	Disease
terms:neg_causes	GLUCOSE TOLERANCE
terms:predisposes	Toxic effect
terms:augments	Liver Transcription, Genetic
terms:neg_produces	Cholic Acid
terms:neg_inhibits	Non-HDL cholesterol
schema:identifier	C1413895\|1582 C0038315\|1582 1582 C1522546\|1582
INTERACTS_WITH	Escherichia coli
is type of	CYP8B1 gene\|CYP8B1
is sameAs of	CYP8B1 gene\|CYP8B1 Sterol 12-alpha-Hydroxylase\|CYP8B1 cyp8b1
is terms:process_of of	Transcription, Genetic
is terms:part_of of	RNA, Messenger 3' Untranslated Regions
is terms:location_of of	Cells Cytoplasm Serum Liver Females Rattus norvegicus Hepatocyte Mus Gallbladder Trees Fetal Liver Cricetinae hepatoma cell Hepatic lobule
is terms:produces of	Transcriptional Activation Excretory function
is terms:interacts_with of	Cholesterol RNA, Messenger Bile Acids Lithocholic Acid Cytochromes Receptors, Nuclear Sterol Regulatory Element Binding Proteins Thyroxine HNF4A Thyroid Hormones Taurocholate Chenodeoxycholic Acid Fluvoxamine TARDBP GLUCOSE-6-PHOSPHATASE Insulin\|INS Protein Tyrosine Phosphatase, Non-Receptor Type 11\|NR0B2

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