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About:
Bcr-Abl tyrosine kinase
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An Entity of Type :
about:enzy#this
, within Data Space :
semmed.demo.openlinksw.com
associated with source
document(s)
Type:
enzy
New Facet based on Instances of this Class
Attributes
Values
label
bcr-abl tyrosine kinase
ASSOCIATED_WITH
Disease
Myeloid Leukemia, Chronic
leukemia
Leukemia, Lymphocytic, Acute
Adhesions
Blast Phase
temperature sensitive mutant
schema:identifier
c1100899
ISA
Phosphotransferases
PART_OF
Cells
CAUSES
Malignant Neoplasms
Myeloid Leukemia, Chronic
DNA Damage
INTERACTS_WITH
imatinib
CRK gene|CRK
Complement System Proteins
Therapeutic agent (substance)
dihydroxyacetone sulfate
PTPNS1 protein, human|SIRPA
STIMULATES
Reactive Oxygen Species
1-Phosphatidylinositol 3-Kinase
STAT5A gene|STAT5A
STAT3 gene|STAT3
DISRUPTS
Apoptosis
Myeloid Leukemia, Chronic
glucose uptake
Glycolysis
NEG_CAUSES
Somatic mutation
AUGMENTS
Phosphorylation
Signal Transduction Pathways
is
COEXISTS_WITH
of
imatinib
CEBPB
is
INHIBITS
of
ESR1 gene|ESR1
imatinib
1-Phosphatidylinositol 3-Kinase
Ceramides
small molecule
Protein-tyrosine kinase inhibitor
Imatinib mesylate
CREB-binding protein|CREB1
Propofol
Fusion Proteins, bcr-abl|ABL1|MTTP
STI571
Catenins
benzamide
is
INTERACTS_WITH
of
imatinib
Adenosine Triphosphate
small molecule
AMN107
CRKL gene|CRKL
is
PRODUCES
of
Wound Healing
Chromosomal translocation
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