About: discoidin domain receptor 2

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About: discoidin domain receptor 2 Goto Sponge NotDistinct Permalink

An Entity of Type : about:c0902406#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
label	discoidin domain receptor 2 tkt ddr2
sameAs	TRANSKETOLASE\|TKT discoidin domain receptor 2\|DDR2
LOCATION_OF	Transcriptional Activation Protein Expression Ectopic Expression mRNA Expression
COEXISTS_WITH	Collagen Osteogen Lectin Fibrillar Collagen SUCLA2 discoidins
ASSOCIATED_WITH	Osteoporosis Glioma Neoplasm progression Degenerative polyarthritis Benign prostatic hypertrophy Corneal Diseases Cartilage damage
schema:identifier	7086 4921 c0902406
ISA	Phosphotransferases PROTEIN KINASE Binding Sites Receptor Protein-Tyrosine Kinases
INHIBITS	receptor collagenase 3 CYP11A1 gene\|CYP11A1 Epithelial Discoidin Domain Receptor 1\|DDR1
PART_OF	Cell surface Chromosomes, Human, Pair 1
CAUSES	Exocytosis Stress Degenerative polyarthritis Malignant neoplasm of stomach
INTERACTS_WITH	Proteins ubiquitin-protein ligase Fibroblasts Osteoclasts Collagen Structure of interstitial cell of Leydig Cell of bone pth SNAI1
STIMULATES	Extracellular Signal Regulated Kinases Gelatinase A Tyrosine Phosphorylation succinate LacZ Genes Cartilage cell
AFFECTS	Transcription, Genetic Neoplasm Metastasis Osteoblasts Signal Transduction Degenerative abnormality Phosphorylation Cell Proliferation Chondrocytes Pulmonary Fibrosis osteoblast differentiation Bone Resorption Cell Cycle Arrest Entire temporomandibular joint Prostate cancer metastatic collagen binding traversing start control point of mitotic cell cycle
compared_with	TRANSKETOLASE
PREDISPOSES	Neoplasm Injury
PREVENTS	tumor growth
DISRUPTS	Tumor Cell Invasion
CONVERTS_TO	Collagen Type II
AUGMENTS	Osteogenesis Motility Bone Resorption cell invasion Carcinoma of Nasopharynx mRNA Expression osteoclast differentiation
PRODUCES	Succinates
NEG_AUGMENTS	Degenerative abnormality
is LOCATION_OF of	Cell surface Cells C0030705 Structure of articular cartilage Body tissue Eye Mus Fibroblasts Chondrocytes Stromal Cells Cartilage cornea Bile duct structure
is COEXISTS_WITH of	Amino Acids
is NEG_AFFECTS of	transketolase activity

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