About: mixed lineage kinase 3

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An Entity of Type : about:c0534507#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
label	mixed lineage kinase 3
LOCATION_OF	Transcription, Genetic Translational Repression
COEXISTS_WITH	Carcinogens matrigel
ASSOCIATED_WITH	Heart failure
schema:identifier	c0534507
INHIBITS	NF-kappa B
CAUSES	Cessation of life
INTERACTS_WITH	Breast Cancer Cell beta catenin CDC42 gene\|CDC42 RAC1 biochanin A upstream kinase
STIMULATES	MAPK8 gene\|MAPK8 CRK protein, human\|CRK NF-kappa B enzyme activity kinase activity ZHX2 beta catenin Dynamin MAP Kinase Kinase Kinase conserved helix-loop-helix ubiquitous kinase Guanine Nucleotide Exchange Factors\|ARHGEF2\|SLC2A4RG
AFFECTS	Down-Regulation Apoptosis Phosphorylation Brain Injury, Ischemic protein kinase C activation
PREVENTS	Functional disorder
DISRUPTS	Transcription, Genetic Phosphorylation
NEG_INTERACTS_WITH	TCF Transcription Factors
NEG_DISRUPTS	JNK activity
is LOCATION_OF of	Epithelial Cells Myocardium Breast Cancer Cell
is ASSOCIATED_WITH of	Vascular proliferation
is INHIBITS of	multicatalytic endopeptidase complex Neurofibromin 2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), human\|COX2\|PTGS2
is INTERACTS_WITH of	Tumor Necrosis Factor Receptor Phosphotransferases Growth Factor dimer RAC-Alpha Serine/Threonine Kinase\|AKT1 CDC42 gene\|CDC42 TNF receptor-associated factor 6\|TRAF6 biochanin A EPHA4 gene\|EPHA4
is STIMULATES of	Tumor Necrosis Factor Receptor ITIH4 tat Genes\|TAT Homologous Protein Tumor Necrosis Factors Neurofibromin 2 TNF receptor-associated factor 2 TNF receptor-associated factor 6\|TRAF6
is AFFECTS of	Ubiquitination
is MEASURES of	Clinical Research

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