About: Tacrolimus Binding Protein 1A|FKBP1A|FKBP1AP1|FKBP1AP2|FKBP1AP3|FKBP1AP4

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About: Tacrolimus Binding Protein 1A|FKBP1A|FKBP1AP1|FKBP1AP2|FKBP1AP3|FKBP1AP4 Goto Sponge NotDistinct Permalink

An Entity of Type : about:c0286862#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
label	tacrolimus binding protein 1a fkbp1a fkbp1ap1 fkbp1ap2 fkbp1ap3 fkbp1ap4
sameAs	FKBP1A about:2282#this about:2283#this about:2284#this about:2285#this
NEG_PART_OF	Oocytes Saccharomyces cerevisiae fungus
LOCATION_OF	Point Mutation
COEXISTS_WITH	Water Binding Sites Sirolimus (substance) RyR2\|RYR1\|RYR2 Hydroxydopamine
NEG_AFFECTS	Trans-Activation (Genetics) ryanodine-sensitive calcium-release channel activity phosphatase activity
ASSOCIATED_WITH	Mutant Alzheimer's Disease
schema:identifier	2280 2282 2283 2284 2285 c0286862
ISA	Binding Protein Pharmaceutical Preparations receptor Peptidylprolyl Isomerase Tacrolimus Binding Proteins cis-trans-Isomerases\|CISH Immunophilins
INHIBITS	Proteins CA2 Sirolimus (substance) Protein Kinase C calreticulin\|CALR Calcineurin phospholamban Peptidylprolyl Isomerase RyR1\|RYR1 DYM tacrolimus binding protein 4\|FKBP4 PRKCA tacrolimus binding protein 1B\|FKBP1A\|FKBP1AP1\|FKBP1AP2\|FKBP1AP3\|FKBP1AP4 calcineurin phosphatase
PART_OF	Kidney Human Protoplasm Animals Saccharomyces cerevisiae Extracellular cell body (neuron) Cytosol Neurites Sarcoplasmic Reticulum Nerve bundle
CAUSES	Functional disorder Cell Cycle Arrest
INTERACTS_WITH	Cells Pharmaceutical Preparations DNA T-Lymphocyte Proteins Phosphotransferases Calcium Channel Soluble ErbB-1\|EGFR inhibitors Sirolimus (substance) Protein Kinase C Ryanodine Receptors Calcineurin FK-506 cis-trans-Isomerases\|CISH RyR1\|RYR1 mTOR Inhibitor Isomerase ITPR1 protein, human\|ITPR1 ACVR1 gene\|ACVR1 tacrolimus binding protein 1B\|FKBP1A\|FKBP1AP1\|FKBP1AP2\|FKBP1AP3\|FKBP1AP4 asip
STIMULATES	Cells P-Glycoprotein Caffeine Ryanodine Receptors RyR2\|RYR1\|RYR2 RyR1\|RYR1 L 688617
AFFECTS	feedback inhibition Mitosis Female genitalia ryanodine-sensitive calcium-release channel activity
compared_with	RyR2\|RYR1\|RYR2
PREDISPOSES	Pathogenesis

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