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asEquivalent
b3s
b3sifp
facets
http://www.w3.org/2002/07/owl#
ldp
oplweb
skos-trans
virtrdf-eturtle-containers
virtrdf-hashtag
virtrdf-ifp
virtrdf-label
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None
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Apply to both subjects and objects (recommended)
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About:
Topotecan
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An Entity of Type :
about:orch#this
, within Data Space :
semmed.demo.openlinksw.com
associated with source
document(s)
Type:
phsu
orch
New Facet based on Instances of this Class
Attributes
Values
label
topotecan
COEXISTS_WITH
TP53 gene|TP53
ABCB1 gene|ABCB1
Human plasma
Cisplatin
Vincristine
Paclitaxel
Liposomes
Fibrin Tissue Adhesive
Methotrexate
Granulocyte Colony-Stimulating Factor
Etoposide
Cyclophosphamide
Carboplatin
gemcitabine
Lactones
ABCG2 gene|ABCG2
Cytotoxic agent
temozolomide
Platinum
chrysin
CD82 gene|CD82
NEG_AFFECTS
Cells
Cell Line
Neoplasm
response
Ovarian Carcinoma
Protein Binding
ASSOCIATED_WITH
Carcinoma, Non-Small-Cell Lung
Dysmyelopoietic Syndromes
Primary carcinoma of the liver cells
Primary central nervous system lymphoma
Small cell carcinoma of lung
DNA Damage
Leukemia, Myelomonocytic, Chronic
Ovarian Carcinoma
Ovarian epithelial cancer recurrent
schema:identifier
c0146224
ISA
Therapeutic procedure
Injection procedure
Pharmacotherapy
Pharmaceutical Preparations
Antineoplastic Agents
Chemotherapy-Oncologic Procedure
Camptothecin
Topoisomerase Inhibitors
Poisons
Camptothecin Analogue
Topoisomerase 1 inhibitor
INHIBITS
Enzymes
Pharmaceutical Preparations
VEGFA
Proteins
Laminin
docetaxel
Antineoplastic Agents
HIF1alpha protein
survivin
Matrix Metalloproteinases
Topoisomerase
aquaporin 5
CCR7
XPO1
ABCC4
CSF1R
CHEK1 gene|CHEK1
CAUSES
Oxidative Stress
Apoptosis
Cytokinesis of the fertilized ovum
Cell Death
Toxic effect
Inactivation
Nausea
Vomiting
cytotoxicity
Cytolysis
DNA Damage
Autophagy
In complete remission
acidification
Senility
Neutropenia
Autocrine Communication
Myelosuppression
INTERACTS_WITH
Membrane Transport Proteins
Pharmaceutical Preparations
DNA
P-Glycoprotein
Cisplatin
Calcium
gefitinib
Cancer Promoting Genes
Etoposide
Chromatin
BRCA1 gene|BRCA1
ABCC2|KLHL1|SYCE1L
ABCG2 gene|ABCG2
quadruplex DNA
ABCG2 protein, human|ABCG2
Serotonin 5-HT-3 Receptor
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