About: involucrin

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An Entity of Type : about:c0063740#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
label	involucrin invs ivl lmln
sameAs	IVL LMLN INVS gene\|INVS
NEG_PART_OF	Cells
LOCATION_OF	Transcription, Genetic Transcriptional Activation Transfection Protein Expression
COEXISTS_WITH	Recombinant Interferon-gamma Paraffin Cadaverine Roxithromycin
ASSOCIATED_WITH	Squamous cell carcinoma Lung Neoplasms Dermatitis, Atopic Psoriasis Actinic keratosis Carcinoma of Nasopharynx Lesion of cervix Bowen's Disease Squamous cell carcinoma, keratinizing Psoriatic plaque Linear lichen planus Precancerous skin lesion Lichen striatus
schema:identifier	3713 89782 27130 c0063740
ISA	Proteins
INHIBITS	Transcription Factor AP-1 pth
PART_OF	Cells Human Epidermis Epidermal cell keratinocyte Structural protein Cytosol Desmosomes Neoplastic Cell Gene Products, env Chromosomes, Human, Pair 1 Epithelial cyst cornified envelope Stratified squamous epithelium envoplakin
CAUSES	Psoriasis
INTERACTS_WITH	Epithelial Cells keratinocyte Ceramides EPHB2\|MAPK1 EP300 protein, human\|EP300 Thiazolidinediones CECR
STIMULATES	Cells RNA Transforming Growth Factor beta keratinocyte Calcium ion Transglutaminases pth KRT5 cholesteryl sulfate keratin 5\|KRT5 KRT17 peptide O-linked N-acetylglucosamine-beta-N-acetylglucosaminidase SPDEF ELOVL4
AFFECTS	Disease Cells Integumentary system Epidermis Transcriptional Regulation Dermatitis, Atopic Lipid Metabolism cornified envelope
compared_with	Therapeutic procedure filaggrin
PREVENTS	Silence
DISRUPTS	Cells T-Lymphocyte [M]Unspecified tumor cell NOS Dermatitis, Atopic
ADMINISTERED_TO	Cells keratinocyte
AUGMENTS	Dermatitis, Atopic Autophagy S Phase Ultraviolet B Radiation
PRODUCES	Collagen
is NEG_LOCATION_OF of	Mucous membrane of bronchus
is LOCATION_OF of	Embryo Cells Cytoplasm C0030705

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