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b3s
b3sifp
facets
http://www.w3.org/2002/07/owl#
ldp
oplweb
skos-trans
virtrdf-eturtle-containers
virtrdf-hashtag
virtrdf-ifp
virtrdf-label
virtrdf-meta-entity-class
None
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About:
cyclopamine
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An Entity of Type :
about:orch#this
, within Data Space :
semmed.demo.openlinksw.com
associated with source
document(s)
Type:
orch
New Facet based on Instances of this Class
Attributes
Values
label
cyclopamine
COEXISTS_WITH
Water
TSC22D3
NEG_AFFECTS
Cell Survival
Cell Proliferation
schema:identifier
c0056789
ISA
Pharmaceutical Preparations
Alkaloids
Veratrum Alkaloids
Plant alkaloid
INHIBITS
Genes
SIRT1
TRANSCRIPTION FACTOR
VEGFA
RNA, Messenger
Insulin-Like Growth Factor I
Alkaloids
Ornithine Decarboxylase
GLI1 gene|GLI1
GLI2 gene|GLI2
Angiopoietin-1
SHH gene|SHH
Untranslated Regions
SMO gene|SMO
GLI Family Protein|GLI1
SMO protein, human|SMO
PTCH1
sonic hedgehog receptors
CAUSES
Apoptosis
Congenital Abnormality
Inflammatory Response
Teratogenesis
Holoprosencephaly
Cell Cycle Arrest
Craniofacial Abnormalities
Limb deformity
Cyclocephaly
cancer regression
INTERACTS_WITH
Chemicals
SMO gene|SMO
SMO protein, human|SMO
sonic hedgehog receptors
polydatin
STIMULATES
VEGF protein, human|VEGFA
Antibodies
Brain-Derived Neurotrophic Factor
Nerve Growth Factors|NGF
ITGAM gene|ITGAM
CD14 gene|CD14
SMO protein, human|SMO
TREATS
Malignant Neoplasms
Neoplasm
Pancreatic carcinoma
pancreatic neoplasm
Helicobacter pylori
Retinal Neovascularization
AFFECTS
Cells
Blood Vessels
Retinal Diseases
Growth
response
Signal Transduction
Fibrosis, Liver
Protein Expression
Drug resistance
cell motility
Embryonic Development
Secondary malignant neoplasm of lung
cholesterol transport
medulloblastoma
Stomodeum
Mouse Supratentorial Primitive Neuroectodermal Tumour
compared_with
CD34 gene|CD34
PREVENTS
Fibrosis, Liver
higher_than
CD34 gene|CD34
DISRUPTS
Cells
Cytoplasm
Extracellular Matrix
Blood Vessels
Hypoxia
Down-Regulation
Cell Line
Growth
Apoptosis
Cell Growth
Signal Transduction
Immunoreactivity
Phosphorylation
Cell Proliferation
Protein Expression
Stem cells
Intracellular Transport
smoothened signaling pathway
NEG_CAUSES
Congenital Abnormality
ADMINISTERED_TO
Cells
Mus
Erinaceidae
AUGMENTS
Cells
Neurons
Growth
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