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About:
11-beta-Hydroxysteroid Dehydrogenases
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about:c0044707#this
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Attributes
Values
label
chst3
11-beta-hydroxysteroid dehydrogenases
sameAs
CHST3
NEG_PART_OF
Fetal Lung
LOCATION_OF
Gene Expression
Mutation
Transcriptional Activation
Point Mutation
COEXISTS_WITH
Sodium
Potassium
Nicotinamide adenine dinucleotide (NAD)
NADP
Enzyme Inhibitors
Mineralocorticoids
Mineralocorticoid Receptor
galactose-6-phosphate dehydrogenase
ASSOCIATED_WITH
Hypertensive disease
Inflammation
Syndrome
Diabetes Mellitus, Non-Insulin-Dependent
Adrenal Cortical Adenoma
Gestational trophoblastic neoplasms
Craniopharyngioma
Mucocutaneous Lymph Node Syndrome
schema:identifier
9469
c0044707
ISA
Enzymes
Proteins
Oxidoreductase
Hydroxysteroid Dehydrogenases
INHIBITS
Glucocorticoids
Hydrocortisone
Glucocorticoid Receptor
Carbenoxolone
11-Hydroxycorticosteroids
PART_OF
Nephrons
Colon
Liver
Placenta
Hepatocyte
Intestines
Infraclass Eutheria
Cerebral cortex
Hypothalamic structure
immortalized cell
Acinar Cell
ileum
Muscle, Smooth, Vascular
Deiter's cell
Fetal Kidney
CAUSES
Hypertensive disease
Inactivation
Congenital adrenal hyperplasia
Hypokalemia
Central obesity
Pseudoaldosteronism
Increased cortisol level
INTERACTS_WITH
Cells
Adrenal Cortex Hormones
Aldosterone
Sodium
Human Cell Line
receptor
Hepatocyte
Osteoblasts
Dexamethasone
Glucocorticoids
NOS3 protein, human|NOS3
Hydrocortisone
Glucocorticoid Receptor
Corticosterone
cofactor
Mineralocorticoids
Cortisone
Mineralocorticoid Receptor
carbonyl compound
nabumetone
STIMULATES
Glucocorticoids
NR3C1 gene|NR3C1
Serum cortisol
CHST3
AFFECTS
Cells
Pathogenesis
Kidney
Liver
Body tissue
Asthma
Inactivation
Human Development
Mesenteric Arteries
Fetal Lung
Hypernatremia
aromatase activity
Abdominal obesity
Fetal Exposure
receptor metabolism
steroid binding
compared_with
Insulin|INS
DISRUPTS
Toxic effect
Lipolysis
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