About: Cytochrome P-450 CYP2E1

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About: Cytochrome P-450 CYP2E1 Goto Sponge NotDistinct Permalink

An Entity of Type : about:c0010763#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
label	cyp2e1 ppig cyp2b6 cytochrome p-450 cyp2e1
sameAs	CYP2E1 gene\|CYP2E1 CYP2B6 Cytochrome P-450 CYP1A1\|PPIG
NEG_PART_OF	Microsomes, Liver
LOCATION_OF	Transcription, Genetic Transcriptional Activation Protein Expression Polymorphism, Genetic
COEXISTS_WITH	Buffers Ethanol Quercetin Mixed Function Oxygenases Ca(2+)-Transporting ATPase CRYGC\|CRYGEP CYP2E1 gene\|CYP2E1 Argipressin\|AVP EMB bufuralol 1'-hydroxylase
NEG_AFFECTS	Microsomes, Liver Liver damage
ASSOCIATED_WITH	Disease Inflammation Malignant neoplasm of breast Oxidative Stress Toxic effect Injury to liver, NOS Non-alcoholic fatty liver Carcinoma of Nasopharynx Hepatotoxicity alcohol effect
schema:identifier	1555 9360 1571 c0010763
ISA	Enzymes Chemicals Iron Proteins Cytochrome P450 Cytochromes Mixed Function Oxygenases liver cytochrome enzymes
INHIBITS	multicatalytic endopeptidase complex Reactive Oxygen Species Glucose Antioxidants Superoxide Dismutase HSP90 Heat-Shock Proteins\|HSP90AA1 Dioxygen Ca(2+)-Transporting ATPase geldanamycin Cytochrome P-450 CYP1A2 NADPH-Ferrihemoprotein Reductase
PART_OF	Cells Kidney Family Liver Brain Human Rattus norvegicus Monkeys Intestines Family suidae Organ Oryctolagus cuniculus Hepatic Microsomes, Liver Tissue membrane Microsomes
CAUSES	Oxidative Stress Toxic effect Fatty degeneration Teratogenesis Alcoholic Liver Diseases Hepatotoxicity
INTERACTS_WITH	Cells TP53 gene\|TP53 Carcinogens Binding Sites Ethanol Salicylic Acid inhibitors Benzene sevoflurane Trichloroethylene Toluene Organic solvent product Ether, Ethyl Xenobiotics Acetaldehyde monomer Acrylamide O-(glucuronic acid 2-sulfate)-(1--3)-O-(2,5)-andydrotalitol 6-sulfate Anticoagulants Halothane Isoenzymes

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