About: CDKN2B gene|CDKN2B

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About: CDKN2B gene|CDKN2B Goto Sponge NotDistinct Permalink

An Entity of Type : http://semmed.demo.openlinksw.com/schemas/Gene#this, within Data Space : semmed.demo.openlinksw.com associated with source document(s)

Attributes	Values
type	Semmed Gene Class
label	cdkn2b sub1 mrpl28 nxt1
sameAs	SUB1 NXT1\|CMTR2 NXT1\|CMTR2 (NIH - Gene) SUB1 (NIH - Gene) about:10573#this cdkn2b (nih - gene)
NEG_PART_OF	Cell Line
LOCATION_OF	Mutation Transcription, Genetic Hypermethylation derepression
COEXISTS_WITH	Tumor Suppressor Genes Agar CDKN2B gene\|CDKN2B CCDC6 gene\|CCDC6 SUV39H1
ASSOCIATED_WITH	Disease osteosarcoma Neoplasm Leukemia, Myelocytic, Acute Tumorigenesis Hematologic Neoplasms Dysmyelopoietic Syndromes Primary carcinoma of the liver cells Leukemia, Lymphocytic, Acute, L1 Lymphoma, Non-Hodgkin's Leukemia, Lymphocytic, Acute Glioblastoma Pituitary Adenoma Hereditary Melanoma
schema:identifier	1030 10923 10573 29107
INHIBITS	CDKN2A gene\|CDKN2A Proliferating Cell Nuclear Antigen\|PCNA Cyclin-Dependent Kinases Gelatinase B Cathepsins B SUV39H1
PART_OF	Cells Mus Herpesvirus 1, Cercopithecine
CAUSES	Cell Cycle Arrest
INTERACTS_WITH	Cells Proteins Tumor Suppressor Genes Promoter (Genetics) Melanoma Cell CD34+ cell HCFC1 KDM2B
STIMULATES	Cells Phosphorylation Transforming Growth Factor beta Dendritic Cells Protein Biosynthesis Cyclin-Dependent Kinases
AFFECTS	osteosarcoma Malignant Neoplasms Carcinogenesis Myeloid Leukemia, Chronic leukemia Lymphoma attenuation Cell Cycle Arrest humoral defense mechanism (sensu Vertebrata) Normal hematopoiesis
compared_with	bactericidal permeability increasing protein
higher_than	bactericidal permeability increasing protein
DISRUPTS	Neoplasm Glioma leukemia cell motility
PRODUCES	nuclear protein
NEG_PRODUCES	peripheral blood
NEG_INHIBITS	CDKN2A gene\|CDKN2A CDKN2A gene\|CDKN2A
is sameAs of	CDKN2B gene\|CDKN2B tyrosine kinase ABL1\|ABL1\|ANPEP\|CTR9\|CHAF1A\|RAB3GAP2\|PIK3R4 cdkn2a cdkn2b
is NEG_PART_OF of	RNA, Messenger
is LOCATION_OF of	Cells C0030705 Cell Line, Tumor Human Cell Line Body tissue Cell Line Human monocyte Bone Marrow Cells Blood specific granule Rodent

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